Background: Queer populations (sexual and gender diverse people, including two-spirit, lesbian, gay, bisexual, trans, and queer) in Canada face significant health disparities, largely driven by stigma related to sexual and gender identities. These inequities are associated with adverse health outcomes. Although a growing body of literature examines stigma reduction, interventions often focus on specific types of queer stigma rather than considering the broader, intersectional experiences of queer people. This scoping review aims to critically explore the current state of queer stigma across the life course in Canada, with an emphasis on understanding their impact, successes, and gaps. Methods: This review will include studies that address interventions aimed at reducing queer-related stigma in Canada. Eligible studies must focus on queer populations and measure outcomes related to stigma reduction. Studies of any design (qualitative, quantitative, mixed methods), published in English or French, and from any year will be considered. A systematic search will be conducted across multiple databases, including Medline-R (Ovid), Embase (Ovid), APA PsycInfo (Ovid), CINAHL (EBSCO), Social Services Abstracts (ProQuest), Social Science Abstracts (ProQuest), and Social Science Citation Index (Web of Science), along with grey literature sources. Two reviewers will independently assess potential articles against the inclusion criteria through two stages: titles and abstracts as well as full-text screening. Data extraction will focus on study characteristics, intervention details, and outcomes related to stigma reduction. Findings will be reported in tables and narrative summaries, guided by the socioecological model and intersectional queer theories. Data will be analyzed to identify trends and gaps in current interventions aimed at addressing queer stigma. Discussion: Using an intersectional queer approach and the socioecological model, this review will identify gaps and strengths in queer stigma programming and interventions across the life course. The broad inclusion criteria and a rigorous approach will account for academic and grey literature, highlighting ongoing treatments, measurement tools, and resources. This extensive data collection will inform future research on queer peoples’ resource and programming needs in Canada. Findings will contribute to workshops development, training modules, and community reports for healthcare providers and community organizations serving queer communities. Systematic review registration: https://doi.org/10.6084/m9.figshare.28523621.v1.