This volume explores the grammatical properties of body-part expressions across a range of languages and language families in the Americas, including Arawakan, Eastern Tukano, Mataguayan, Panoan, and Takanan. Expressions denoting parts of the body often exhibit specific grammatical properties that are intrinsically related to their semantics, and frequently appear in dedicated constructions, many of which are found exclusively in association with these expressions. Following a detailed introduction and discussion of the foundations of body-part grammar, the chapters in the first part of the book investigate categorialization, lexicalization, and the semantic processes associated with body-part expressions. In the second part of the book, contributors investigate specific grammatical properties of body-part expressions, such as inalienability, incorporation, possessive constructions, prefixation, topicality, and word-formation strategies. The volume draws on data from lesser-known languages that are often under-represented in comparative work, and makes a significant contribution not only to the linguistics of the Americas and the typology of body-part expressions, but also to typological studies more broadly, and to historical, comparative, and anthropological linguistics.